Paul Garcia, MD, PHD
Anesthesiology
Accepting New Patients
Overview
Academic Appointments
- Associate Professor of Anesthesiology
Administrative Titles
- Division Chief of Neuroanesthesia
Hospital Affiliations
- NewYork-Presbyterian / Columbia University Irving Medical Center
Gender
- Male
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Credentials & Experience
Education & Training
- Georgia Institute of Technology
- Emory University School of Medicine
- Residency: Emory University Hospital
Board Certifications
- Anesthesiology
Honors & Awards
- Teaching Award, CUMC Neuroanesthesia Division; June 2019 (awarded by anesthesiology residents)
- Outstanding Research Faculty of Emory School of Medicine. Presented on Researcher Appreciation Day; September 2017
- Best Abstract, Clinical Neurosciences, American Society of Anesthesiologists Annual Meeting, Chicago; October 2016
- Nomination and Induction as Active Member into Association of University Anesthesiologists (AUA); December 2015
- Emory University School of Medicine Faculty Award, "Hidden Gem", Celebration of Faculty Excellence Ceremony; October 2015, in appreciation of mentoring students and residents in scholarship.
- Best Abstract, Experimental Neurosciences, American Society of Anesthesiologists Annual Meeting, San Diego; October 2015
- Featured Poster Presentation, 4th Annual Science of Graduate Medical Education Day, Emory University School of Medicine; June 2013
- Mentor Award, Systems-Based Learning Project for Emory Anesthesiology Residents; June 2012.
- Featured Abstract, 65th PGA of the New York State Society of Anesthesiologists. Oral presentation in a Best Abstracts of the Meeting session; December 2011.
- Top 5% User Accessed Review, Faculty of 1000, F1000.com; 2011.
- Top 10% User Accessed Review, Faculty of 1000, F1000.com; 2010, 2012.
- Resident Research, Third Place Winner. American Society of Anesthesiology Annual Meeting. New Orleans; October 2009
- Best Abstract, Honorable Mention. Research was recognized at the International Society for Anaesthetic Pharmacology. New Orleans; October 2009
- First Place for Resident Research, 62nd PGA, New York State Society of Anesthesiologists; December 2008
- FAER / Abbott Resident Scholar, American Society of Anesthesiology; 2008.
- Medical Student Research Fellow, Foundation for Anesthesia Education and Research; 2005
- President’s Fellowship, Georgia Institute of Technology; 1999 – 2004
- Outstanding Mentor Award, Research Experience for Undergraduates Program, Georgia Institute of Technology. Recognized for mentoring of undergraduate students in research; May 2000.
- National Hispanic Scholar Award; 1991 – 1995
- Thomas J. Watson Scholarship, IBM; 1991 – 1995
- Inductee, Tau Beta Pi, Engineering Honors Society; 1993
- Inductee, Eta Kappa Nu, Electrical Engineering Honors Society; 1993
Research
Selected Publications
- Mansouri MT, Fidler JA, Meng QC, Eckenhoff RG, GarcÃa PS. Sex effects on behavioral markers of emergence from propofol and isoflurane anesthesia in rats.Behav Brain Res. 2019 Jul 23;367:59-67. doi: 10.1016/j.bbr.2019.03.029. Epub 2019 Mar 18. PubMed PMID: 30898682.
- Voss LJ, GarcÃa PS, Hentschke H, Banks MI. Understanding the Effects of General Anesthetics on Cortical Network Activity Using Ex Vivo Preparations.Anesthesiology. 2019 Jun;130(6):1049-1063. doi: 10.1097/ALN.0000000000002554. PubMed PMID: 30694851; PubMed Central PMCID: PMC6520142.
- Hesse S, Kreuzer M, Hight D, Gaskell A, Devari P, Singh D, Taylor NB, Whalin MK, Lee S, Sleigh JW, GarcÃa PS. Association of electroencephalogram trajectories during emergence from anaesthesia with delirium in the postanaesthesia care unit: an early sign of postoperative complications. Br J Anaesth. 2019 May;122(5):622-634. doi: 10.1016/j.bja.2018.09.016. Epub 2018 Oct 25. PubMed PMID: 30915984; PubMed Central PMCID: PMC6465086.
- Hight DF, Gaskell AL, Kreuzer M, Voss LJ, GarcÃa PS, Sleigh JW. Transient electroencephalographic alpha power loss during maintenance of general anaesthesia. Br J Anaesth. 2019 May;122(5):635-642. doi: 10.1016/j.bja.2018.11.029. Epub 2019 Jan 30. PubMed PMID: 30915994.
- Kelz MB, GarcÃa PS, Mashour GA, Solt K. Escape From Oblivion: Neural Mechanisms of Emergence From General Anesthesia. Anesth Analg. 2019 Apr;128(4):726-736. doi: 10.1213/ANE.0000000000004006. PubMed PMID: 30883418.
- O'Reilly-Shah VN, Hemani S, Davari P, Glowka L, Gebhardt E, Hill L, Lee S, Master VA, Rodriguez AD, GarcÃa PS. A Preoperative Cognitive Screening Test Predicts Increased Length of Stay in a Frail Population: A Retrospective Case-Control Study.Anesth Analg. 2019 Mar 11;. doi: 10.1213/ANE.0000000000004103. [Epub ahead of print] PubMed PMID: 30882522.
- Gaskell A, Pullon R, Hight D, Termaat J, Mans G, Voss L, Kreuzer M, Schmid S, Kratzer S, Rodriguez A, Schneider G, Garcia P, Sleigh J. Modulation of frontal EEG alpha oscillations during maintenance and emergence phases of general anaesthesia to improve early neurocognitive recovery in older patients: protocol for a randomised controlled trial. Trials. 2019 Feb 22;20(1):146. doi: 10.1186/s13063-019-3178-x. PubMed PMID: 30795794; PubMed Central PMCID: PMC6387545.
- Mees L, Fidler J, Kreuzer M, Fu J, Pardue MT, GarcÃa PS. Faster emergence behavior from ketamine/xylazine anesthesia with atipamezole versus yohimbine. PLoS One. 2018;13(10):e0199087. doi: 10.1371/journal.pone.0199087. eCollection 2018. PubMed PMID: 30372437; PubMed Central PMCID: PMC6205597.
- Safavynia SA, Arora S, Pryor KO, GarcÃa PS. An update on postoperative delirium: Clinical features, neuropathogenesis, and perioperative management. Curr Anesthesiol Rep. 2018 Jul 4;8(3):252-262. PubMed PMID: 30555281; PubMed Central PMCID: PMC6290904.
- Hight DF, Sleigh J, Winders JD, Voss LJ, Gaskell AL, Rodriguez AD, GarcÃa PS.Inattentive Delirium vs. Disorganized Thinking: A New Axis to Subcategorize PACU Delirium. Front Syst Neurosci. 2018;12:22. doi: 10.3389/fnsys.2018.00022. eCollection 2018. PubMed PMID: 29875640; PubMed Central PMCID: PMC5974154.
- Yang E, Kreuzer M, Hesse S, Davari P, Lee SC, GarcÃa PS. Infrared pupillometry helps to detect and predict delirium in the post-anesthesia care unit. J Clin Monit Comput. 2018 Apr;32(2):359-368. doi: 10.1007/s10877-017-0009-z. Epub 2017 Mar 8. PubMed PMID: 28275978.
- LaBarbera V, GarcÃa PS, Bliwise DL, Trotti LM. Central Disorders of Hypersomnolence, Restless Legs Syndrome, and Surgery With General Anesthesia: Patient Perceptions. Front Hum Neurosci. 2018;12:99. doi: 10.3389/fnhum.2018.00099. eCollection 2018. PubMed PMID: 29615884; PubMed Central PMCID: PMC5869929.
- McGregor KM, Crosson B, Mammino K, Omar J, GarcÃa PS, Nocera JR. Influences of 12-Week Physical Activity Interventions on TMS Measures of Cortical Network Inhibition and Upper Extremity Motor Performance in Older Adults-A Feasibility Study. Front Aging Neurosci. 2017;9:422. doi: 10.3389/fnagi.2017.00422. eCollection 2017. PubMed PMID: 29354049; PubMed Central PMCID: PMC5758495.
- Kratzer S, Mattusch C, Garcia PS, Schmid S, Kochs E, Rammes G, Schneider G, Kreuzer M, Haseneder R. Propofol and Sevoflurane Differentially Modulate Cortical Depolarization following Electric Stimulation of the Ventrobasal Thalamus. Front Comput Neurosci. 2017;11:109. doi: 10.3389/fncom.2017.00109. eCollection 2017. PubMed PMID: 29321737; PubMed Central PMCID: PMC5732174.
- Makhani SS, Kim FY, Liu Y, Ye Z, Li JL, Revenig LM, Vaughan CP, Johnson TM 2nd, GarcÃa PS, Ogan K, Master VA. Cognitive Impairment and Overall Survival in Frail Surgical Patients. J Am Coll Surg. 2017 Nov;225(5):590-600.e1. doi: 10.1016/j.jamcollsurg.2017.07.1066. Epub 2017 Aug 4. PubMed PMID: 28826805; PubMed Central PMCID: PMC5995330.
- Ciavatta VT, Bichler EK, Speigel IA, Elder CC, Teng SL, Tyor WR, GarcÃa PS. In vitro and Ex vivo Neurotoxic Effects of Efavirenz are Greater than Those of Other Common Antiretrovirals. Neurochem Res. 2017 Nov;42(11):3220-3232. doi: 10.1007/s11064-017-2358-x. Epub 2017 Aug 2. PubMed PMID: 28770436.
- Garcia PS, Rothman DL, Fitzpatrick SM. Waking Up to a New Model for Studying Neural Systems: What Emergence from Unconscious States Can Reveal about Brain Organization. Front Syst Neurosci. 2017;11:78. doi: 10.3389/fnsys.2017.00078. eCollection 2017. PubMed PMID: 29089871; PubMed Central PMCID: PMC5651010.
- Rha J, Jones SK, Fidler J, Banerjee A, Leung SW, Morris KJ, Wong JC, Inglis GAS, Shapiro L, Deng Q, Cutler AA, Hanif AM, Pardue MT, Schaffer A, Seyfried NT, Moberg KH, Bassell GJ, Escayg A, GarcÃa PS, Corbett AH. The RNA-binding protein, ZC3H14, is required for proper poly(A) tail length control, expression of synaptic proteins, and brain function in mice. Hum Mol Genet. 2017 Oct 1;26(19):3663-3681. doi: 10.1093/hmg/ddx248. PubMed PMID: 28666327; PubMed Central PMCID: PMC5886104.
- Speigel I, Bichler EK, GarcÃa PS. The Influence of Regional Distribution and Pharmacologic Specificity of GABAAR Subtype Expression on Anesthesia and Emergence. Front Syst Neurosci. 2017;11:58. doi: 10.3389/fnsys.2017.00058. eCollection 2017. Review. PubMed PMID: 28878632; PubMed Central PMCID: PMC5572268.
- Hight DF, Voss LJ, GarcÃa PS, Sleigh JW. Electromyographic activation reveals cortical and sub-cortical dissociation during emergence from general anesthesia.J Clin Monit Comput. 2017 Aug;31(4):813-823. doi: 10.1007/s10877-016-9911-z. Epub 2016 Jul 21. PubMed PMID: 27444893.
- Hernandez BA, Lindroth H, Rowley P, Boncyk C, Raz A, Gaskell A, GarcÃa PS, Sleigh J, Sanders RD. Post-anaesthesia care unit delirium: incidence, risk factors and associated adverse outcomes. Br J Anaesth. 2017 Aug 1;119(2):288-290. doi: 10.1093/bja/aex197. PubMed PMID: 28854553.
- Kreuzer M, Whalin MK, Hesse SDW, Riso MA, GarcÃa PS. Anesthetic Management of a Patient With Multiple Previous Episodes of Postanesthesia Care Unit Delirium: A Case Report. A A Case Rep. 2017 Jun 15;8(12):311-315. doi: 10.1213/XAA.0000000000000497. PubMed PMID: 28252543.
- Müller JN, Kreuzer M, GarcÃa PS, Schneider G, Hautmann H. Monitoring depth of sedation: evaluating the agreement between the Bispectral Index, qCON and the Entropy Module's State Entropy during flexible bronchoscopy. Minerva Anestesiol.2017 Jun;83(6):563-573. doi: 10.23736/S0375-9393.17.11262-9. Epub 2017 Feb 8. PubMed PMID: 28177205.
- Moody OA, Talwar S, Jenkins MA, Freeman AA, Trotti LM, GarcÃa PS, Bliwise D, Lynch JW, Cherson B, Hernandez EM, Feldman N, Saini P, Rye DB, Jenkins A. Rigor, reproducibility, and in vitro cerebrospinal fluid assays: The devil in the details.Ann Neurol. 2017 Jun;81(6):904-907. doi: 10.1002/ana.24940. Epub 2017 Jun 1. PubMed PMID: 28440033; PubMed Central PMCID: PMC5639705.
- Hight D, Voss LJ, Garcia PS, Sleigh J. Changes in Alpha Frequency and Power of the Electroencephalogram during Volatile-Based General Anesthesia. Front Syst Neurosci. 2017;11:36. doi: 10.3389/fnsys.2017.00036. eCollection 2017. PubMed PMID: 28611600; PubMed Central PMCID: PMC5446988.
- Kreuzer M, Schneider G, GarcÃa PS. The Input Is Reflected in the Output: Evaluating Neurophysiologic Monitors With Simulated Data. Anesth Analg. 2017 May;124(5):1734-1735. doi: 10.1213/ANE.0000000000001958. PubMed PMID: 28319506.
- Gooch JL, King C, Francis CE, Garcia PS, Bai Y. Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity. PLoS One. 2017;12(4):e0175242. doi: 10.1371/journal.pone.0175242. eCollection 2017. PubMed PMID: 28414804; PubMed Central PMCID: PMC5393575.
- Garcia P, Sleigh J. Ketamine: A Drug at War with Itself. Anesthesiology. 2017 Mar;126(3):371-372. doi: 10.1097/ALN.0000000000001513. PubMed PMID: 28099245.
- Safavynia SA, Keating G, Speigel I, Fidler JA, Kreuzer M, Rye DB, Jenkins A, GarcÃa PS. In Reply. Anesthesiology. 2017 Feb;126(2):352-353. doi: 10.1097/ALN.0000000000001446. PubMed PMID: 28098616; PubMed Central PMCID: PMC5340312.
- Bichler EK, Elder CC, GarcÃa PS. Clarithromycin increases neuronal excitability in CA3 pyramidal neurons through a reduction in GABAergic signaling. J Neurophysiol. 2017 Jan 1;117(1):93-103. doi: 10.1152/jn.00134.2016. Epub 2016 Oct 12. PubMed PMID: 27733592; PubMed Central PMCID: PMC5209546.
- Safavynia SA, Keating G, Speigel I, Fidler JA, Kreuzer M, Rye DB, Jenkins A, GarcÃa PS. Effects of γ-Aminobutyric Acid Type A Receptor Modulation by Flumazenil on Emergence from General Anesthesia. Anesthesiology. 2016 Jul;125(1):147-58. doi: 10.1097/ALN.0000000000001134. PubMed PMID: 27111534; PubMed Central PMCID: PMC5326685.
- Berger M, GarcÃa PS. Anesthetic Suppression of Thalamic High-Frequency Oscillations: Evidence that the Thalamus Is More Than Just a Gateway to Consciousness?. Anesth Analg. 2016 Jun;122(6):1737-9. doi: 10.1213/ANE.0000000000001207. PubMed PMID: 27195617; PubMed Central PMCID: PMC4874518.
- Woodbury A, Soong SN, Fishman D, GarcÃa PS. Complementary and alternative medicine therapies for the anesthesiologist and pain practitioner: a narrative review. Can J Anaesth. 2016 Jan;63(1):69-85. doi: 10.1007/s12630-015-0506-9. Epub 2015 Oct 14. Review. PubMed PMID: 26467546.
- GarcÃa PS, Duggan EW, McCullough IL, Lee SC, Fishman D. Postanesthesia Care for the Elderly Patient. Clin Ther. 2015 Dec 1;37(12):2651-65. doi: 10.1016/j.clinthera.2015.10.018. Epub 2015 Nov 17. Review. PubMed PMID: 26598176.
- Wu F, Torre E, Cuellar-Giraldo D, Cheng L, Yi H, Bichler EK, GarcÃa PS, Yepes M.Tissue-type plasminogen activator triggers the synaptic vesicle cycle in cerebral cortical neurons. J Cereb Blood Flow Metab. 2015 Dec;35(12):1966-76. doi: 10.1038/jcbfm.2015.155. Epub 2015 Jul 1. PubMed PMID: 26126868; PubMed Central PMCID: PMC4671117.
- Whalin MK, Kreuzer M, Halenda KM, GarcÃa PS. Missed Opportunities for Intervention in a Patient With Prolonged Postoperative Delirium. Clin Ther. 2015 Dec 1;37(12):2706-10. doi: 10.1016/j.clinthera.2015.09.012. Epub 2015 Oct 20. PubMed PMID: 26492795.
- Woodbury A, Yu SP, Chen D, Gu X, Lee JH, Zhang J, Espinera A, GarcÃa PS, Wei L.Honokiol for the Treatment of Neonatal Pain and Prevention of Consequent Neurobehavioral Disorders. J Nat Prod. 2015 Nov 25;78(11):2531-6. doi: 10.1021/acs.jnatprod.5b00225. Epub 2015 Nov 5. PubMed PMID: 26539813; PubMed Central PMCID: PMC6133305.
- GarcÃa PS, Ciavatta VT, Fidler JA, Woodbury A, Levy JH, Tyor WR. Concentration-Dependent Dual Role of Thrombin in Protection of Cultured Rat Cortical Neurons.Neurochem Res. 2015 Nov;40(11):2220-9. doi: 10.1007/s11064-015-1711-1. Epub 2015 Sep 5. PubMed PMID: 26342829; PubMed Central PMCID: PMC4644093.
- Chander D, GarcÃa PS, MacColl JN, Illing S, Sleigh JW. Electroencephalographic variation during end maintenance and emergence from surgical anesthesia. PLoS One. 2014;9(9):e106291. doi: 10.1371/journal.pone.0106291. eCollection 2014. PubMed PMID: 25264892; PubMed Central PMCID: PMC4180055.
- Hight DF, Dadok VM, Szeri AJ, GarcÃa PS, Voss L, Sleigh JW. Emergence from general anesthesia and the sleep-manifold. Front Syst Neurosci. 2014;8:146. doi: 10.3389/fnsys.2014.00146. eCollection 2014. PubMed PMID: 25165436; PubMed Central PMCID: PMC4131673.
- Trotti LM, Saini P, Freeman AA, Bliwise DL, GarcÃa PS, Jenkins A, Rye DB.Improvement in daytime sleepiness with clarithromycin in patients with GABA-related hypersomnia: Clinical experience. J Psychopharmacol. 2014 Jul;28(7):697-702. doi: 10.1177/0269881113515062. Epub 2013 Dec 3. PubMed PMID: 24306133.
- Arora SS, Gooch JL, GarcÃa PS. Postoperative cognitive dysfunction, Alzheimer's disease, and anesthesia. Int J Neurosci. 2014 Apr;124(4):236-42. doi: 10.3109/00207454.2013.833919. Epub 2013 Sep 27. Review. PubMed PMID: 23931049.
- Woodbury A, Yu SP, Wei L, GarcÃa P. Neuro-modulating effects of honokiol: a review. Front Neurol. 2013;4:130. doi: 10.3389/fneur.2013.00130. eCollection 2013. Review. PubMed PMID: 24062717; PubMed Central PMCID: PMC3769637.
- Farish SE, Garcia PS. Capnography Primer for Oral and Maxillofacial Surgery: Review and Technical Considerations. J Anesth Clin Res. 2013 Mar 18;4(3):295. doi: 10.4172/2155-6148.1000295. PubMed PMID: 24459603; PubMed Central PMCID: PMC3897173.
- Farish SE, Garcia PS. Capnography Primer for Oral and Maxillofacial Surgery: Review and Technical Considerations. Journal of Anesthesia & Clinical Research. 2013 March; 4(3):295. doi: 10.4172/2155-6148.1000295.
- Rye DB, Bliwise DL, Parker K, Trotti LM, Saini P, Fairley J, Freeman A, Garcia PS, Owens MJ, Ritchie JC, Jenkins A. Modulation of vigilance in the primary hypersomnias by endogenous enhancement of GABAA receptors. Sci Transl Med.2012 Nov 21;4(161):161ra151. doi: 10.1126/scitranslmed.3004685. PubMed PMID: 23175709.
- Thaler A, Siry R, Cai L, Garcia PS, Chen L, Liu R. Memory Loss, Alzheimer's Disease and General Anesthesia: A Preoperative Concern. Journal of Anesthesia & Clinical Research. 2012 February; 3(2):192. doi: 10.4172/2155-6148.1000192.
- Liu R, GarcÃa PS, Fleisher LA. Interest in Anesthesia as Reflected by Keyword Searches using Common Search Engines. J Anesth Clin Res. 2012 Jan 23;3(1). PubMed PMID: 23853739; PubMed Central PMCID: PMC3707513.
- GarcÃa PS, Cabbabe A, Kambadur R, Nicholas G, Csete M. Brief-reports: elevated myostatin levels in patients with liver disease: a potential contributor to skeletal muscle wasting. Anesth Analg. 2010 Sep;111(3):707-9. doi: 10.1213/ANE.0b013e3181eac1c9. Epub 2010 Aug 4. PubMed PMID: 20686014.
- GarcÃa PS, Gulati A, Levy JH. The role of thrombin and protease-activated receptors in pain mechanisms. Thromb Haemost. 2010 Jun;103(6):1145-51. doi: 10.1160/TH09-12-0848. Epub 2010 Apr 29. Review. PubMed PMID: 20431855.
- Garcia PS, Kolesky SE, Jenkins A. General anesthetic actions on GABA(A) receptors.Curr Neuropharmacol. 2010 Mar;8(1):2-9. doi: 10.2174/157015910790909502. PubMed PMID: 20808541; PubMed Central PMCID: PMC2866459.
For a complete list of publications, please visit PubMed.gov